Dietary Supplement Manufacuturing & Nutraceutical Insights

Origin of CoQ10

Origin of CoQ10

CoQ10, or otherwise known as Coenzyme Q10 or Ubiquinol, as the name suggests, is found everywhere in the body, and is needed to convert nutrients into energy that the body uses for all its functions. Not surprisingly CoQ10 is concentrated in the heart, liver, lungs, muscular system, and brain as these organs require the most energy. It is a vitamin-like, fatty substance which functions as a co-enzyme. CoQ10 also exerts a protective action on cell walls protecting them from electrical charges that occur during the chemical process of energy generation.

CoQ10 was initially introduced into the market as a supplement for athletes to increase endurance and stamina. It then became popular predominantly for its role in supporting heart health and as a healthy-aging ingredient. Thirty years of research shows that CoQ10 is a star player, performing an important role in many essential functions of the body and in bioenergetics. More research suggests it could be useful in:

  • Boosting energy levels
  • Heart health
  • Antioxidant functions
  • Brain health
  • Mood health
  • Skin Health (including photo-aging)
  • Periodontal health
  • Vision
  • Immune health
  • Regulating healthy blood sugar levels
  • Fertility in men

Scientists have discovered that too little of CoQ10 in the body means less energy production and impact on cellular health. Since CoQ10 is supportive to the functions of all organs, a deficiency may result in less than optimal health.

Who Needs Coenzyme Q10?

Scientific research has shown that several factors that may accelerate the decline of Coenzyme Q10 levels in the body.

  • Clinical trials show patients who have been prescribed statins also show a deficiency in Coenzyme Q10. Evidence strongly suggests that statins reduce the levels of Coenzyme Q10 causing a deficiency of this vitamin.
  • There are about 13 million people who take statins in the United States alone, and the number of people prescribed statins are expected to rise in the near future.
  • High metabolic rates, endurance exercises, and hard physical labor can deplete the Coenzyme Q10 storage levels in the body.
  • Prolonged use of NSAIDS (such as ibuprofen), may also deplete levels of Coenzyme Q10 in the body.

Surging Demand for Ubiquinol CoQ10

From 2001 to 2006 Ubiquinol CoQ10 supplements have experienced a growth rate of 13 percent. In 2007, the IRI (market research firm) noted a 19 percent increase in the dollar sales volume at retail outlets. It also noted that unit sales had increased by 9 percent. Currently, estimates suggest there could be more than six million consumers of CoQ10 ubiquinol supplements.

Research from the Freedonia Group predicts that nutrients such as CoQ10, along with glucosamine and chondroitin will generate the fastest growth (6.4 percent a year) in 2008-2013.

Major suppliers of CoQ10 have opened up manufacturing units within the United States. This has led to greater availability of CoQ10 in the nutraceutical market and opened a wider market for CoQ10 functional foods, beverages and dietary supplements. In spite of the economic downturn, key suppliers have recorded high demand for CoQ10.

CoQ10 Delivery Forms

In 2006, Ubiquinol, a reduced form of CoQ10 was introduced into the market. This led to more popular forms such as water-soluble CoQ10, CoQ10 in matrix or beadlet form. These new forms can offer more stability, easier formulation, and may be highly bioavailable. Nano-grade CoQ10 can be easily incorporated into beverages. Tablets, capsules, and powders are the common delivery forms.

CoQ10 Supplements

Popular uses of CoQ10 are in cosmetics, cosmeceuticals (beauty and skincare supplements), healthy-aging supplements, cardiovascular health, cognitive health, and various age-related health concerns. It can be manufactured alone or in combination with other nutraceuticals for an innovative formula that reaches your specific demographics.

July 1st, 2009

About the Author:

Andrew Goldman

Andrew Goldman is the Vice President of Marketing for NutraScience Labs. In this role, he leverages his 10+ years of experience to develop cutting-edge initiatives for our firm.