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Men’s Health Supplements

Last updated: January-18,2023

The Men's Health Supplements Guide

While everyone should do all they can to promote a healthy lifestyle at any age, men and women have different nutritional requirements. Of course, hormonal differences exist, and the aging process affects men and women differently.

Diet is only one aspect of good men's health and nutrition. Men may not always obtain sufficient amounts of a few essential vitamins and nutrients even if they think they’re eating a healthy diet. There are also lifestyle differences to consider. Men's health and wellness goals often require incorporating a few natural supplements into their daily routine for the best possible outcome.

While diet and exercise are critical, there are benefits to be gained by upping the ante on nutrition whenever possible. Apart from a healthy diet, a regular exercise regimen, adequate sleep, and an effective stress management strategy all contribute to a higher quality of life.

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  1. Market Opportunities and Trends In 2022-23
  2. Top Health Concerns Faced by Men
  3. Workout Supplements for Men
  4. Fertility Supplements for Men
  5. Testosterone Supplements for Men
  6. Joint Supplements for Men
  7. Hair Supplements for Men
  8. Probiotics Benefits for Men
  9. Mineral and Vitamin Supplements for Men
  10. Fiber Supplement for Men
  11. Conclusion

Men's Health Supplements - Market Opportunities and Trends In 2022-23

The dietary supplements market is expected to be worth $155.2 billion in 2022, with a 7.3% CAGR to reach $220.8 billion by 2027. The increasing health awareness among consumers is expected to drive the growth of the dietary supplement market.

Traditional healthy-aging marketers have focused on female consumers, but in recent years, men’s health supplements have grown in popularity as men turn to supplementation to help maintain their energy and fitness levels.

According to the Council for Responsible Nutrition, 73 percent of all men in the United States use dietary supplements to support their health, a higher percentage than ever before. According to the report, 42 percent of male supplement users are interested in products that provide overall health and wellness benefits.

The market for supplements for men is a fertile ground for innovation, with a growing demographic of baby boomers looking to maintain their vitality and an active lifestyle. Recent ingredient developments have demonstrated that there is still room for new formats and formulas. Expect new opportunities for men's health ingredients to emerge as more men strive to stay fit and healthy.

Mens Supplement Market Trend

Source: Keywordtool.io

The increase in traffic for terms such as “men’s health supplements” and “supplements for men’s health” has seen a sharp rise at the beginning of 2022, proving that men's health supplements are trending.

Mens Supplement Search Trend

Source: Keywordtool.io

There has been a noticeable rise in the total search volume of some of the most prominent queries associated with men’s health supplements.

Top Health Concerns Faced by Men

Men who do not fuel their bodies with sufficient amounts of the proper vitamins and nutrients may negatively impact their energy levels, testosterone levels, sexual health, immunity, bones and joints, mental health, and hair health, to mention a few.

There is no such thing as a "perfect" diet, and no one can do it flawlessly every day. This is where men's dietary supplements come in. A daily supplement plan can help men get the right amount of essential vitamins while also working to improve their health and nutrition.

This guide is all about the best supplements for men, addressing top men's health issues. This includes supplements to support workout/bodybuilding, testosterone, fertility, sexual health, joint health, and hair growth. In addition, this guide will address probiotics’ benefits for men and other vitamins and supplements for men's health.

NSL - Infographic - Top Supplements for Health Concerns faced by Men

Workout Supplements for Men

There are dozens of potential workout supplement options for men and muscle-building supplements for men. However, I've chosen to write about beta-alanine, creatine, and whey protein since they each have a significant body of research to support their effectiveness.


The amino acid beta-alanine (β -alanine) stands out as one of the few supplements with solid scientific evidence proving its effectiveness in the worlds of bodybuilding, performance nutrition, and sports supplements.

β-alanine has been identified as the rate-limiting precursor to carnosine synthesis [1] [2] and has consistently increased carnosine levels in human skeletal muscle. The results are considerable performance improvements.

According to a position paper on beta-alanine published in the Journal of the International Society of Sports Nutrition,[3] the effects of β-alanine supplementation and its corresponding increase in muscle carnosine concentrations include:

  1. improved exercise performance, with more pronounced impacts in open end-point tasks/time trials lasting 1 to 4 minutes
  2. reduction of neuromuscular fatigue (particularly in older subjects)
  3. possible progress in tactical performance

β-alanine has been used in doses of 1.6-6.4 grams daily as 1-8 divided doses for up to 12 weeks. In older adults, beta-alanine is often used in daily doses of 2.4-3.2 grams.


Creatine is a non-protein amino acid compound found in red meat and seafood, as well as our own muscles. It is essential in the regeneration of ATP (adenosine triphosphate)—the “energy currency” of our muscles.  

Creatine monohydrate is the most used supplemental form of this compound. It is also the most common form of creatine used in human studies. These findings have repeatedly shown that this widely known ergogenic supplement increases muscular creatine levels, muscle mass, and strength.

Creatine supplementation has been shown in studies to promote injury prevention, post-exercise recovery, rehabilitation, thermoregulation, and neuroprotection, in addition to athletic performance.[4] 

Creatine has been shown in research to help with muscle mass gain, where the involvement of creatine in the muscle was shown to act as an anabolic signal for muscle building, where creatine acts as the chemical signal coupling increased muscular activity and increased muscular tissue production.[5] [6] 

Similarly, the presence of creatine in the muscle temporarily increases its water content, giving it a "pumped" appearance. Of course, the increase in water does not imply an increase in muscle tissue, but many people like the look. Typically, 5-8 grams of creatine monohydrate is consumed daily.

Whey Protein

Whey protein, derived from whey (a byproduct of cheese manufacturing), contains more essential amino acids than other protein sources.[7] Whey protein is high in BCAA (Branched Chain Amino Acids), with a typical content of 24%.[8] It has the highest biological value of other protein tested (particularly whey protein isolate), and numerous studies have demonstrated its effectiveness in assisting in the development of lean muscle massas part of a training program.[9] [10] [11] 

Clinical studies show that consuming whey protein isolate daily for 6-10 weeks in conjunction with strength training increased lean body mass, strength, and muscle hypertrophy compared to placebo.[12] [13] [14] 

In a ten-week double-blind study,[15] recreational bodybuilders enhanced their regular diet with whey protein isolate or casein (another milk protein). The whey protein isolate group gained significant lean mass compared to the other protein group (11 lbs vs. 1.76 lbs) and lost significant fat mass compared to the other protein group (-3.3 lbs vs. +0.44 lbs). The bodybuilders also attained substantial improvements in strength.

Whey protein isolate also resulted in greater stimulation of protein synthesis[16] compared to other protein sources tested, laying the groundwork for muscle mass preservation and production. Several studies have found that whey protein supplementation is beneficial in enhancing the effects of resistance exercise, especially when supplementation takes place in the hours surrounding exercise training.[17] 

The American College of Sports Medicine, the Academy of Nutrition and Dietetics, and Dietitians of Canada all recommend 1.2 to 2.0 grams of protein per kilogram of body weight per day, and whey protein can contribute to that. At least 20 g of whey protein daily is typically used.

Fertility Supplements for Men

When considering sex supplements for men to help address their fertility and sexual health issues, those that help support the healthy production of sperm, nitric oxide, and testosterone take center stage. Since there is a separate section on testosterone supplements for men in this guide, this section will deal with those supplements supporting the production of sperm and nitric oxide production.


Secreted from sedimentary rocks (mainly in the Himalayas), Shilajit is a pale brown to blackish-brown exudate composed of rock humus, rock minerals, and organic substances that have been compressed by layers of rock mixed with marine organisms and microbial metabolites.[18] 

It is used extensively by Ayurvedic physicians for various conditions, including managing male reproductive issues [19] [20]. Furthermore, Shilajit has a vast history of use in Ayurvedic medicine as an aphrodisiac[21] [22] [23] [24] [25], and its safety has been well recorded based on human and animal studies.[26] 

In a 90-day clinical trial,[27] the effects of 100 mg Shilajit (as PrimaVie® purified Shilajit) twice daily in 28 infertile male patients with oligospermia (a condition with low sperm concentration) resulted in significant (P < 0.001) improvement in various parameters, including 37.6% increase in sperm mobility, 61.4% increase in total sperm count, 12.4-17.4% increase in motility (after different time intervals), 18.9% increase in normal sperm count. There was also a significant 23.5% increase in serum testosterone (P < 0.001) and 9.4% increase in FSH (P < 0.05) levels.


Sluggish circulation may translate into an inadequate blood supply to the genital region making it more difficult to achieve and sustain an erection. Furthermore, insufficient endogenous biochemical nitric oxide (NO) production can exacerbate this problem since adequate NO is essential for vasodilatation of blood vessels and erectile function.

The amino acid L-arginine is a precursor (building material) for the synthesis of NO[28]. Supplemental sources of L-arginine appear to augment NO production[29], with the result being a measurable increase in blood flow[30] (i.e., vasodilatation). Because penile erection involves the relaxation of the cavernous smooth muscle induced by nitric oxide, it might be expected that L-arginine supplementation would aid erectile function.

Studies have shown that when supplementing with L-arginine in doses of 5 grams[31] or 2.8 grams[32] daily, men were either responders or non-responders (presumably based upon their levels of nitric oxide, i.e., those with low nitric oxide would be responders). The responders experienced significant improvements in erectile and sexual function.


Another amino acid, L-citrulline, has similar effects to L-arginine. In fact, many of L-citrulline's functions stem primarily from its ability to increase plasma levels of arginine endogenously (in the human body)[33]. Moreover, citrulline appears to increase plasma arginine levels more effectively than the amino acid arginine itself [34]. This is the basis for the use of citrulline to increase nitric oxide.

More importantly, in a single-blind, placebo-controlled study[35], supplementation with 1.5 g/day of L-citrulline resulted in an improvement in the erection hardness score in 50% of the men tested (P < 0.01).

Testosterone Supplements for Men

Testosterone (T) levels in men decline with age, and a significant proportion of men over the age of 60 have serum T levels that are lower than the lower limits for young adult men (age 20-30 years).[36] 

According to some studies [37], men’s total T levels begin to decline gradually in their thirties at a rate of about 1% per year. In contrast, other studies[38] show an average annual decrease of 1-2% in total T levels, with an even faster decline in free T. This is associated with a reduction in libido and sexual activity.


Several nutraceuticals can aid in the promotion of healthy testosterone levels. The root of ashwagandha (Withania somnifera), used in Ayurvedic medicine [39] for over 3000 years, is one of my favorites.

The effects of ashwagandha root extract (KSM-66® ashwagandha, 675 mg/d in three doses, n=21) or placebo (n=25) on sperm activity and serum hormone levels were studies in 46 men in a one 90-day, two-arm, double-blind, randomized, placebo-controlled, parallel-group study[40]. Ashwagandha resulted in a 17% increase in testosterone (P0.01), a 167% increase in sperm count (P0.0001), a 53% increase in sperm volume (P0.0001), and a 57% increase in sperm motility (P0.0001).

Another 8-week randomized, prospective, double-blind, placebo-controlled clinical study[41] was carried out to investigate the effects of this same ashwagandha root extract (one 300 mg capsule, twice daily) or placebo on muscle endurance and strength, size and recovery, testosterone, and body fat in 50 healthy and physically active males (18-45 years old, n=25 for each group) with little resistance training experience.

The results showed that ashwagandha supplementation outperformed the placebo. Serum testosterone was increased by 15% (P0.05), muscle strength (bench press) was significantly increased (P0.001), muscle size (arm) was significantly increased (P0.05), and reduced body fat percentage significantly (P0.05).

Eurycoma longifolia

Eurycoma longifolia Jack (aka Long Jack or Tongkat Ali) is an herb of South-East Asian origin, traditionally used as an aphrodisiac to enhance male sexual performance[42] [43] [44] [45] [46]. Modern scientific research has also demonstrated this advantage because of increasing serum testosterone levels.[47] [48] 

However, it is important to note that human clinical research has been performed on a specific proprietary extract known as LJ100®. Human clinical studies on LJ100® have been shown at various dosage levels, but 200 mg/day showed the most benefits.

Studies included both open-label trials and controlled trials. Depending on the study, LJ100® increased testosterone by 16.4-71.5% [49] [50] [51], and sexual health results increased significantly,[52] [53] as much as 91%.[54]

Vitamin D

Three different cross-sectional studies involving thousands of men have demonstrated that higher vitamin D levels are linked to higher levels of testosterone, and lower levels of estrogen in men.[55] [56] [57] 

Regarding supplementation research, 54 healthy but overweight men participating in a weight reduction plan participated in a randomized and controlled trial[58]. The participants received either 3,332 IU vitamin D daily for one year or a placebo. Initially, vitamin D levels were deficient, and testosterone levels were at the bottom of the reference range.

The results showed that the vitamin D group had a 25% increase in total testosterone levels. The placebo group showed no significant change in any testosterone measure.

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Joint Supplements for Men

Whether due to aging, work, or exercise, joint issues can impact men, slowing them down and making their quality of life just that much less [59]. As with the other men’s health categories, there are many potential ingredients for inclusion in joint supplements for men.

Cucumber Extract

Arguably, the most prevalent joint ingredients are glucosamine and chondroitin—but are they the best? Probably not. Consider a relatively new cucumber-based extract. Cucumber has long been recognized for benefits to red, tired, and puffy eyes and was introduced to Britain by the Roman soldiers, who presumably used it to ease sore feet or other aches and pains.

A 6-month (180-day) randomly chosen, double-blind, parallel-group clinical trial was conducted to assess the efficacy of this cucumber fruit water extract (Q-Actin™) against glucosamine-chondroitin (GC) in promoting joint comfort. It included 122 patients (56 men and 66 women) aged 40 to 75 years.

The study included two groups of 61 participants each. The GC group received 1,350 mg of GC twice daily (2,700 mg/day), while the Q-Actin™ group received 10 mg of cucumber extract twice daily (20 mg/day). The tests were performed at the start (Day 0) and on Days 30, 60, 90, 120, 150, and 180.

The Q-Actin™ group improved joint comfort by 29.8% and 70.39% on Days 30 and 180, respectively, compared to only 14.8% and 33.7% in the GC group.

During the trial period, no adverse effects were reported. The researchers concluded that Q-actin was more productive than glucosamine-chondroitin in helping to promote joint comfort and consequently improving function.

Undenatured Type II Collagen

In 2013 the results of a randomized, double-blind, placebo-controlled study [60] were presented during a conference at the Scripts Center for Integrative Medicine.  Fifty-five subjects reporting joint discomfort associated with strenuous exercise received either a placebo or an undenatured type II collagen derived from chicken sternum cartilage known as UC-II® (40 mg, which provides 10 mg undenatured type-II collagen per day) for 120 days.

The results were that, compared to placebo, UC-II® supplementation significantly improved joint flexibility, allowed subjects to exercise longer before experiencing initial joint discomfort, and allowed subjects to exercise longer before experiencing maximum joint discomfort. There were no significant changes in the placebo group. 

Andrographis paniculata

Andrographis paniculata is an herb with a history of use in both Ayurvedic and traditional Chinese medicine. Called the “king of bitters” in Asia, Andrographis contains several bitter constituents which appear to have both immune-modulating and anti-inflammatory activity.[61] 

Recent research has shown that andrographolide (a compound in Andrographis) inhibits enzymes that would otherwise break down collagen materials) found in cartilage.[62] Research has shown that 300 mg/day of Andrographis paniculata extract provides 50% total andrographolides (150 mg/twice daily as ParActin®), helping promote joint comfort.

Furthermore, a study[63] was conducted in which mice were treated with Andrographis extract (ParActin®, HP Ingredients) for three months and tested for muscle recovery after exercise. The results showed that the extract reduced pain and inflammation associated with the exercise and reduced muscle protein breakdown. This suggests that Andrographis extract may help muscle recovery in the gym.

Hair Supplements for Men

Women aren’t the only gender who want to promote hair growth and improve the appearance of their hair. Luckily, some nutraceuticals are ideal as hair growth supplements for men.

Pomegranate Extract

A longitudinal, randomized clinical trial[64] was conducted to evaluate the properties and tolerability of a whole fruit pomegranate water extract known as Pomanox™ P30. In the study, two capsules/day providing 366 mg of the extract were used in 20 males aged between 34 and 60.  

The main objective was the evaluation of hair growth by photo trichogram. Secondary objectives were anti-hair loss capacity (strength of the hair) by pull-test. Participants were divided into two groups of 10. In the Pomanox™, the results were:

Hair pull-test:

A significant reduction in the numbers of hair lost during the hair pull test over the course of the 3 visits:

Visit 1 -    6.25 hairs
Visit 2 -    4.3 hairs
Visit 3 -    3.7 hairs

Photo trichogram:

A significant improvement in hair density over the course of the 3 visits:

Visit 1 -    60.5
Visit 2 -    62.8
Visit 3 -    66.5

A significant reduction in the percentage of thin hair (diameter less than 40 um) over the course of the 3 visits:

Visit 1 -    24.46%
Visit 2 -    20.42%
Visit 3 -    19.47%

A significant improvement in hair growth rate over the course of the 3 visits:

Visit 1 -    0.298
Visit 2 -    0.3203
Visit 3 -    0.3409


In short, the pomegranate extracts effectively reduced hair loss and thinness while improving hair density and growth rate

Beta-sitosterol and Saw Palmetto Extract

Testosterone can be converted in the body into dihydrotestosterone (DHT). DHT is thought to cause hair follicles to miniaturize, which isn’t the best thing to happen if you want to maintain a healthy head of hair.

The botanical supplements saw palmetto and beta-sitosterol had been shown to slow down the production of a particular enzyme called 5-alpha reductase, which converts testosterone into DHT. If you’re wondering if this impacts hair, consider the following.

Nineteen men were given one softgel containing 50 mg beta-sitosterol, and 200 mg saw palmetto extract (standardized to 85% to 95% lipsterolic content) twice a day or a matching placebo softgel for an average of 4.6 months.

Based on the investigative staff's assessment of change in the patient's scalp hair growth from baseline, treatment with the active study formula demonstrated that 60% of subjects rated as "improved" at the final visit compared to baseline. In contrast, only 11% in the placebo group were rated as "improved."[65] So the answer seems to be “Yes.”

Probiotics Benefits for Men

One of the biggest mistakes I see in the formulation of probiotic products is the “everything but the kitchen sink” approach. In other words, the inclusion of multiple probiotic strains in a single capsule—but insufficient amounts of any single strain to have any real benefit. Think about it.

If studies show that a specific probiotic strain is effective at a dose of 10 billion CFU, why would you create a formula with only 1 billion CFU of that strain? It’s like expecting an 81 mg baby aspirin to gid rid of your headache when the correct dose is two 325 mg aspirin tablets (650 mg total).

My point is that you’re better off using a clinically relevant dose of one probiotic strain than a sub-potent dose of several strains, which is not likely to have the desired effect. That being the case, here are some well-researched strains to consider for men’s health.

Lactobacillus rhamnosus GG

Lactobacillus rhamnosus GG (or Lactobacillus GG for short) is one of the single most well-researched probiotic strains, has good resistance to stomach acid and bile, it grows well and adheres effectively in the intestines.[66] 

Studies show that Lactobacillus GG provides excellent support for your immune system and helps keep your digestive system running smoothly—and you feeling your best—by helping to restore the natural balance of good bacteria in your intestines. [67] [68] [69] [70] [71] [72] [73] [74] [75] [76] [77] [78] [79] 

Furthermore, Lactobacillus GG may help promote normal serotonin metabolism in the intestines[80]. That’s important since serotonin is important for maintaining a healthy mood and for the regulation of appetite[81] [82] [83]. A standard dose of Lactobacillus GG is 5 billion CFU.

Bacillus coagulans

Many probiotic strains are destroyed by stomach acid before they ever reach the gut—and if they do reach the gut, the probiotics may be destroyed by bile. Fortunately, spore-forming probiotic bacteria can overcome this problem because the spore itself is a protective encasement that allows almost indefinite storage until it is ready to be consumed and can survive transit through the stomach intact.[84] 

One such spore-forming probiotic is called Bacillus coagulans. Research indicates that the spore-like protein coating on B. coagulans “allows it to survive stomach acid, reach the small intestine, germinate, and multiply.”[85] In addition, research has also shown that B. coagulans can tolerate bile, allowing it to survive within the small intestine as well[86]. So now that we know that it survives in the GI tract, what does it do for you once it gets there?

A 60-day, human intervention, open-label, single-center, phase II clinical study[87] was conducted to investigate whether B. coagulans in capsule form would promote healthy serum cholesterol levels in 30 patients (15 male, 15 female). The patients were equally divided into 3 groups.

One group received a daily dose of two B. coagulans capsules, each providing 10 billion CFU. Another group received a daily dose of two B. coagulans capsules, each providing 20 billion CFU. B. coagulans. The third group received a standard cholesterol medication. Results showed that both doses had a highly desirable impact on both total and HDL cholesterol levels.

Bifidobacterium lactis HN019

Bifidobacterium lactis HN019 is a probiotic strain that is particularly good for promoting gastrointestinal comfort. Research shows it helps relieve occasional acid indigestion and heartburn and promotes upper gastrointestinal comfort. In addition, Bifidobacterium lactis HN019 has been clinically tested to help reduce occasional reflux and promote upper gastrointestinal comfort.[88] 

Furthermore, this probiotic strain has been clinically tested to help prevent constipation[89] [90]. Also of significance is that it has been safety-tested and verified[91]. A standard dose of Bifidobacterium lactis HN019 is 1.8 billion CFU.

Mineral and Vitamin Supplements for Men

Although men and women need all the same vitamins and minerals and other nutritional substances like fiber, some of these are especially critical and beneficial for men. These should be considered daily supplements for men's health.

Vitamin D

Should there be a vitamin D supplement for men? Consider that a group of urinary functions referred to as LUTS (lower urinary tract symptoms) includes incomplete bladder emptying, urination frequency (< 2 hours), stopping and starting urination, the urgency to urinate, weak stream, straining or push to urinate, nocturia (need to wake and pass urine at night).[92] [93] [94] [95] [96] 

It turns out that low vitamin D levels are associated with an increased risk for LUTS. This was demonstrated in the National Health and Nutrition Examination Survey, where many men with LUTS (89%, n = 1241) had insufficient vitamin D levels (<30 ng/mL), of whom 55% (n = 684) had deficient vitamin D levels (<20 ng/mL).

Among the 1388 (58%) men with LUTS data and vitamin D levels, 48% (n = 666) had at least 1 LUTS. The researchers concluded, “Vitamin D deficiency and insufficiency are common among adult men in the United States, and vitamin D deficiency is linked to moderate-severe UI and the occurrence of at least one LUTS.”[97]

As previously mentioned in the section on testosterone supplements, vitamin D also plays a role in maintaining healthy testosterone levels.


How about a zinc supplement for men? Well, zinc is important for the male reproductive system. In fact, zinc content is high in the adult testis, and the prostate has a higher zinc concentration than any other body organ. In human seminal plasma, zinc is found in much higher concentrations than other body fluids. This means that with each ejaculation, men lose some zinc.

In a study where men were fed a zinc-controlled diet and then supplemented with varying doses of zinc for 35 days, seminal loss accounted for 9% of total body zinc loss when only 1.4 mg of zinc was consumed.14 In addition, 1.4 mg of zinc daily decreased semen volumes and serum testosterone concentrations compared to when a daily dose of 10.4 mg was given.

Compared with 10.4 mg of zinc daily, lower doses decreased the total semen zinc loss per ejaculate. In addition, low dietary zinc status has been associated with low circulating concentrations of testosterone.[98] 

Conversely, research[99] has shown that male subjects with normal testosterone levels had significantly higher zinc levels than those with low testosterone levels. Zinc supplementation in marginally zinc-deficient older men for six months resulted in close to a doubling of serum testosterone levels.[100] 

In addition, research[101] has shown that zinc supplementation prevented a decrease in testosterone levels after exercising, and other groups of men as well.[102] [103] [104] [105] 

Fiber Supplement for Men

Most people are aware that fiber plays an important role in helping to keep us regular. But it also plays a role in helping to suppress appetite—a consideration for many men who want to eat less and lose weight. The way it works is that fiber absorbs water or other liquids and expands in the stomach, helping to create a full feeling.

While this is generally true of any fiber, there are some types that perform better than others for this purpose.  One such type is oligofructose and oligofructose-enriched inulin (OEI). Both oligofructose and inulin are soluble fibers, and oligofructose is also identified as a functional fiber which means that it has additional beneficial physiological effects in humans.[106] 

In one double-blind, randomized, placebo-controlled, cross-over trial,[107] thirty-six overweight and obese men and women consumed either 12 g/day OEI or placebo for three weeks as two 6 g supplements dissolved in a beverage with breakfast and lunch. The result was that the subjects using the OEI consumed significantly fewer calories.

In another randomized double-blind, cross-over study,[108] 31 healthy men and women received 10 g oligofructose, 16 g oligofructose, or 16 g placebo daily for 13 days. The result was that the subjects consumed significantly fewer calories with 16 g/ day of oligofructose. In a third randomized, double-blind, parallel, placebo-controlled trial,[109] 10 healthy adults received either 16 g/ day OEI or 16 g/ day placebo for 2 weeks. Results showed that the OEI treatment lowered hunger rates and ate fewer calories than the placebo group.

Additional studies have shown similar results[110] [111] [112] [113]. Furthermore, other research has shown that supplementation with OEI provided additional benefits: it helped improve calcium absorption [114] [115] [116] [117], and it acted as a prebiotic that promoted the growth of healthy Bifidobacteria probiotic colonies in the gut. [118] [119] [120] [121]

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There is a plethora of potential men’s health supplements. The ones mentioned in this guide are only scratching the surface, but they are nevertheless all excellent candidates. Any of these can be considered for use in products for men’s health.

If you’re interested in creating a men’s health dietary supplement like the ones I’ve included in this document, I encourage you to contact NutraScience Labs. Our team possesses over 120 years of nutraceutical industry experience and has helped more than 2,300 brands custom manufacture high-quality dietary supplement products.

To get started, call 855-492-7388 to speak with one of our representatives or request your free manufacturing price quote.  


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[2] Dunnett M, Harris RC. Influence of oral beta-alanine and L-histidine supplementation on the carnosine content of the gluteus medius. Equine Vet J Suppl. 1999 Jul; (30):499-504.

[3] Trexler ET, Smith-Ryan AE, Stout JR, et al. International society of sports nutrition position stand: Beta-Alanine. J Int Soc Sports Nutr. 2015; 12: 30.

[4] Kreider RB, Kalman DS, Antonio J, et al. International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. JISSN. 2017;14:18.

[5] Fry D, Morales M. A reexamination of the effects of creatine on muscle protein synthesis in tissue culture. J Cell Biol. 1980; 84(2): 294-297.

[6] Ingwall JS, Weiner CD, Morales ED, Stockdale FE. Specificity of creatine in the control of muscle protein synthesis. J Cell Biol. 1974;62(1): 145-151.

[7] Cribb PJ, Wiliams AD, Carey MF, Hayes A. The effect of whey isolate and resistance training on strength, body composition, and plasma glutamine. Int J Sport Nutr Exerc Metab 2006;16:494-509.

[8] Whey Protein monograph. Natural Medicines Comprehensive Database. Retrieved February 24, 2009

[9] Cribb PJ, Wiliams AD, Carey MF, Hayes A. The effect of whey isolate and resistance training on strength, body composition, and plasma glutamine. Int J Sport Nutr Exerc Metab 2006;16:494-509.

[10] Cribb PJ, Williams AD, Stathis CG, et al. Effects of whey isolate, creatine, and resistance training on muscle hypertrophy. Med Sci Sports Exerc 2007;39:298-307.

[11] Candow DG, Burke NC, Smith-Palmer T, Burke DG. Effect of whey and soy protein supplementation combined with resistance training in young adults. Int J Sport Nutr Exerc Metab 2006;16:233-44.

[12] Cribb PJ, Wiliams AD, Carey MF, Hayes A. The effect of whey isolate and resistance training on strength, body composition, and plasma glutamine. Int J Sport Nutr Exerc Metab 2006;16:494-509.

[13] Cribb PJ, Williams AD, Stathis CG, et al. Effects of whey isolate, creatine, and resistance training on muscle hypertrophy. Med Sci Sports Exerc 2007;39:298-307.

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January 16th, 2023

About the Author:

Gene Bruno

Gene Bruno, MS, MHS, RH(AHG) - Mr. Bruno possesses over 43 years of dietary supplement industry experience. With a Master's degree in nutrition and a second Master's degree in herbal medicine, he has a proven track record of formulating innovative, evidence-based dietary supplements. Mr. Bruno currently serves as both the Senior Director of Product Innovation at Twinlab Corporation and Professor of Nutraceutical Science at Huntington University of Health Sciences.