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Last updated: October-30,2020

Probiotics & Microbiome Dietary Supplements - What You Need to Know

Have you been paying attention to microbiomes lately? With a growing body of research suggesting that those micro-flora may be the key players in how our bodies process food, nutrients and dietary supplements, now may be the perfect time to start.  There's no denying that the human body is a complex thing. In fact, it's so complex that it seems for every scientific breakthrough made or question answered – a new, previously unrecognized (but no less engaging) question is raised.

Mirroring and fueled (at least in part) by the increased interest in probiotics, researchers exploring the intricacies of gut/digestive health have admitted – time and again – that there's still so much that we don't yet understand or know when it comes to how our gut functions and how it may influence other aspects of our health. 

Among all the different components of gut health being thrown in to the spotlight as of late, microbiomes and the human microbiome seem to have earned a center stage spot.

Definition Time: What is a microbiome, exactly?

Before we dive into the growing relationship between microbiomes/microbiome research, probiotics, and the supplement industry – let's take a moment to make sure that we're all on the same page when it comes to understanding what a microbiome actually is.

Generally, the term microbiome refers to an ecosystem of microorganisms existing in a unique environment. More often than not, the "unique environment" being referred to happens to be the human body. In recent years and months, both scientific and consumer interest in microbiomes and the human microbiome have skyrocketed. But why make a claim when you can demonstrate it, right? Take a gander at how the interest of computer users in the US has changed over the last decade (courtesy of Google Trends):

Since 2011, user generated interest in the term "microbiome" has increased nearly tenfold! Now that we've laid out conversational ground work, let's take a closer look at how microbiomes and probiotics are affecting the dietary supplement industry.

Probiotics, Microbiomes, & Dietary Supplements: What You Need to Know

Currently, there are dozens of different conversations in place – each one dealing with a different way in which the gut microbiome may influence our health and how our body works with nutrients and supplements. Of those conversations, here are three that we feel the nutraceutical industry should (as of this current moment) be paying particular attention to:

Links between Gut Microbiome, Metabolic Issues & Obesity

More specifically, there's been a good deal of research suggesting that our gut microbiome may play a key role and the onset, course, and treatment of metabolic diseases and obesity issues. While there's still plenty more research that needs to be done – the long-term implications of firmly established links between the gut microbiome and metabolic health/obesity could be tremendous (especially for anyone working within the world of weight-loss supplements and nutrition).

Links between Gut Microbiome and Probiotics

One of the more interesting topics within the gut microbiome/probiotics relationship has been the suggestion that probiotics may be able to help those with a poor or compromised microbiome. In the not-too-distant future it may be possible to do a number of different things, including:

  • Link specific microbiome profiles/deficiencies with specific symptoms and conditions.
  • Mitigate the severity or frequency of these microbiome-induced symptoms or conditions by paring them with a unique and complementary probiotic strain.

If breakthroughs like these were to become a reality over the course of the next 5-10 years (realities that are definitely within the current realm of possibility), they would have the potential to fundamentally alter the way that we use, manufacturer, and consume probiotic supplements.

Links between Gut Microbiome and Cognitive Health

Are you familiar with the "gut-brain axis"? How about the "gut-brain connection" or the "gut-brain link"? Acknowledging that all three terms are different ways of saying the same things, the link between the gut and the brain has been recognized by scientists for decades. In recent years, researchers have found evidence that changes to the microbiome may have a major impact on the biochemical neural highway linking our brain and our gut. In particular, there's a growing body of evidence suggesting a link between emotional and mental health issues (like depression and anxiety) and a healthy gut microbiome profile.

Why should the nutraceutical industry pay attention to the gut microbiome and microbiome research?

It's impossible to know what tomorrow may bring – but in this industry, tomorrow's success is always linked to what happens today. As researchers continue to research the links between the gut microbiome and human health, there's no denying that the potential long-term implications for the dietary supplement industry are massive.

Related Reading: Top Supplement Types According to Users - Infographic


  1. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566439/
  2.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539293/
  3. http://www.ncbi.nlm.nih.gov/pubmed/20974015
  4. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367209/
April 27th, 2018

About the Author:

Melissa DellaBartolomea

Melissa DellaBartolomea was the resident Content Marketing Specialist at NutraScience Labs from February 2016 to July 2018. Driven by a passion for the world of written, visual, and digital media, she's dedicated herself to keeping up with all things nutraceutical. From ingredient insights to the latest in contract manufacturing regulations and trends, her mission is to provide our readers (like you) with the stories and knowledge they need to fuel long-term growth and nutraceutical industry success.